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    Expert In Cell-free Protein Expression Technology

    Expert In Cell-free Protein Expression Technology

    Rapid, Efficient, And High-throughput Protein Preparation Optimization

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    无细胞蛋白表达技术专家

    无细胞蛋白表达技术专家

    快速、高效、高通量蛋白制备

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    About Us

    Suzhou PLD Technology Co., Ltd. specializes in cell-free protein synthesis technology, dedicated to accelerating the development of novel biopharmaceuticals, personalized medicines, and advanced diagnostic tools through this pioneering platform. Leveraging its expertise, Suzhou PLD Technology enables the swift and efficient production of intricate proteins in a controlled setting, precisely tailored to meet specific therapeutic and diagnostic requirements. Our sophisticated facilities and groundbreaking technologies form a solid basis for conducting high-quality research and guaranteeing the reliability and safety of our products. The company offers a comprehensive suite of cell-free protein expression tools, protein reagents, and customized services tailored to biomedical enterprises and research institutions.

    2017 year

    The company was established in

    700 Ten thousand

    Registered capital

    Leading Enterprises in Suzhou Park

    Specialized cell-free protein expression biotechnology company

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    Ultra-fast expression

    The target protein can be detected in as little as one hour, and the entire process—from gene to protein—takes only a few hours, significantly shortening the R&D cycle compared with traditional cell‑expression systems, which typically require 1–2 weeks.

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    Open and controllable

    The cell-free system is fully open, allowing for the flexible incorporation of non-canonical amino acids, detergents, cofactors, and other components, thereby enabling precise control over the protein synthesis environment.

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    High-throughput screening

    It is easily amenable to automation on 96- or 384-well plates, enabling the preparation of thousands of protein variants per day for screening, making it particularly well suited for AI‑driven macromolecular drug discovery and enzyme engineering.

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    Difficult-to-express protein

    It can efficiently express membrane proteins, toxic proteins, and aggregation-prone proteins that are difficult to handle using conventional methods, and has successfully produced key targets such as CXCR4 and CLDN18.2.

    Products & Services

    We offer high-quality biotechnology products to meet your diverse needs in life sciences research and biopharmaceutical development.

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    PLD Cell-Free Protein Expression Product Line

    PLD Cell-Free Protein Expression Product Line

    We provide cell-free protein expression kits in diverse specifications, catering to expression requirements of standard proteins, membrane proteins, full-length antibodies and other biomolecules.
    Full-Length Transmembrane Protein Products

    Full-Length Transmembrane Protein Products

    Custom-designed for drug target proteins including GPCRs and ion channels, our products adopt proprietary detergent or nanodisc technologies to achieve soluble protein expression.
    Difficult-to-Express Protein Expression & Purification Service

    Difficult-to-Express Protein Expression & Purification Service

    Boasting a success rate exceeding 96%, our service enables efficient and rapid synthesis of membrane proteins, inclusion body proteins and cytotoxic proteins, serving as an optimal solution for challenging protein expression projects.
    Site-Specific Incorporation of Unnatural Amino Acids Service

    Site-Specific Incorporation of Unnatural Amino Acids Service

    Unnatural amino acids can be precisely inserted into designated sites of target proteins to endow proteins with novel functionalities. This technology supports the development of next-generation ADC drugs, enzyme evolution research and other applications.

    Application

    We have successfully developed a high-performance, industrial-grade cell-free protein synthesis platform that can be widely applied in biopharmaceuticals, industrial enzyme preparations, research, and many other fields.

    Biopharmaceutical research and development

    Biopharmaceutical research and development

    Leveraging cell-free protein expression and non-canonical amino acid technologies, we rapidly synthesize biopharmaceutical molecules such as antibodies, vaccine antigens, and recombinant proteins, thereby efficiently shortening the R&D cycle and accelerating the translation of innovative drugs.

    AI-based protein screening

    AI-based protein screening

    A high-throughput cell-free expression system, seamlessly integrated with AI‑driven protein design workflows, enables rapid synthesis of AI‑designed protein variants and functional proteins, establishing a closed loop of “AI design–rapid expression–efficient screening” to accelerate the R&D and iterative development of enzyme engineering, antibody therapeutics, and functional proteins.

    Development of difficult protein expression

    Development of difficult protein expression

    Overcoming the traditional bottlenecks of cellular expression, we enable the efficient production of challenging proteins—including membrane proteins, inclusion bodies, and toxic proteins—providing a one-stop expression platform for both research and industrial applications.

    News

    Record Perotin’s development updates and share the excitement!

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    Free opportunity to “break the membrane”! Custom membrane protein expression services—available for a limited time; don’t miss out!

    Free opportunity to “break the membrane”! Custom membrane protein expression services—available for a limited time; don’t miss out!

    2026

    06-17

    Live Stream Reservation | A Revolution in Protein R&D Efficiency: Cell-Free Protein Expression Meets High-Throughput BLI, Ensuring AI Is No Longer Starved for Data

    The rapid advancement of AI-driven drug discovery is driving an exponential surge in demand for high-quality molecular interaction data. However, traditional protein‑production methods suffer from low throughput and lengthy assay cycles, making them the most significant bottleneck between wet‑lab experiments and AI models. How can we achieve end-to-end automation, spanning rapid protein preparation to high‑throughput affinity screening? And how can we ensure that wet‑lab assays deliver high‑quality inputs that meet the data‑hungry requirements of AI systems?

    2026

    07-09

    CFPS is Bridging the "Last Mile" of Protein Design

    2026

    07-09

    Cell-free expression opens new avenues for studying membrane protein function.

    Perotin Bio, leveraging its proprietary cell-free protein expression platform, has established a comprehensive product portfolio ranging from assay kits to end-to-end membrane protein expression services. By incorporating folding‑assisting factors such as nanodiscs and detergents into the expression system, the company effectively enhances the solubility and functional activity of challenging membrane proteins, including multi‑transmembrane receptors, transporters, and ion channels. The company has achieved expression levels and activity at structural‑resolution quality for numerous membrane protein targets, significantly shortening the R&D cycle for research clients—from gene to functional protein.

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