Technical Service
Develop and produce rare proteins and traditional difficult to produce proteins, achieving high-end "intelligent manufacturing" of drug proteins
“AI+CFPS” protein synthesis service
The One-Stop Service Platform of "AI Prediction and Design + Efficient CFPS and Screening + Function Validation"
AI + cell-free protein expression: building an end-to-end innovative solution spanning design to validation.
In drug development and life science research, the structural design of biological macromolecules and the rapid preparation of functional proteins are crucial links for breakthrough and innovation. PLD Technology, in collaboration with Primary Biotech, integrates internationally leading AI algorithms and cell-free protein synthesis (CFPS) technology to create a full-process solution of "AI Prediction and Design - Efficient Synthesis and Screening - Function Validation", accelerating the process from target discovery to protein application.
CFPS enables rapid and low-cost protein production, and is highly versatile and flexible due to its open reaction environment, which is free of cellular structural and physiological constraints, and allows all intracellular metabolism and synthesis processes to be easily accomplished in a common reaction vessel. When combined with AI algorithms, this integration achieves rapid iteration through the "AI Prediction & Design → Rapid CFPS & Screening → Algorithm Feedback & Optimization" cycle. This accelerates complex protein design and high-throughput screening, providing an efficient and adaptable technical pathway for drug development.
AI-Predicted & Design
Efficient Synthesis &Screening
Function Validation
Service Introduction
AI Prediction and Antigen-Antibody Complex Structure Design + CFPS High-Throughput Antibody Screening
Leveraging deep learning models, we predict antigen-antibody complex structures, potential binding interfaces, and hotspot residues critical for binding interactions based on input antigen/antibody sequences. Integrated with PLD's CFPS technology, target antigens/antibodies can be synthesized within 24 hours, seamlessly bridging AI predictions with wet-lab validation to significantly reduce trial-and-error costs in antibody development. PLD's high-throughput automated protein/peptide synthesis and screening workstation processes thousands of samples daily, enabling large-scale synthesis of mutant proteins and drastically shortening R&D timelines.
Service Advantages
Empowered by high-precision AI algorithms, with rapid iterative feedback loops, it drives diversified drug discovery and development.
High-precision underlying algorithm
Codock once won the first place in the Protein/RNA-Ligand Complex Structure Prediction (Ligand) track of the CASP15 competition. The prediction accuracy of the ligand binding conformation, with an RMSD as low as 0.56Å, can improve the success rate of drug design.
Efficient closed loop between AI and experiments
It can achieve rapid iteration of "AI Prediction & Design - CFPS Rapid Synthesis & Screening - Feedback & Algorithm Optimization", shortening the R&D cycle.
Broad Application scenarios
It supports the development of small molecule / PROTAC / antibody drugs, as well as the analysis of the interaction between vaccine antigens and antibodies, meeting diversified R&D needs.
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Contact Information
Service Hotline: +86-512-67900128
Customer Service: order@sz-pld.tech
Business Cooperation: bd@sz-pld.tech
Address: Room 302, Building 1, Weili Medical Science and Technology Park, No. 69 Jiepu Road, Suzhou Industrial Park
