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Unnatural amino acids (UAAs) technology expands the genetic code, enabling researchers to incorporate chemically distinct functional groups into proteins—groups that do not occur in nature—thereby offering unprecedented opportunities for protein labeling, structural analysis, modulation of catalytic activity, and the design of novel materials [1]. As the UAA toolbox continues to grow, this approach is emerging as a pivotal technological platform in structural biology, protein engineering, and biopharmaceutical development.
2026/02/02
From January 15 to 17, the second “Science and Innovation · Liuye Lake” Synthetic Biology Manufacturing Innovation and Entrepreneurship Competition was successfully held in Changde, Hunan. After multiple rounds of intense competition and rigorous expert evaluation, Suzhou Perotin Biotechnology Co., Ltd. (hereinafter referred to as “Perotin Bio”) stood out among 338 high‑quality entries from around the world, winning the “Most Promising Award” thanks to its cutting‑edge technological breakthroughs in cell‑free protein expression and significant industrialization potential. This achievement underscores the company’s robust innovative capabilities and highlights the vibrant vitality of China’s synthetic biology sector.
2026/01/26
As the 11th E‑Trade Bio Industry Exhibition (BIOCHINA 2026) draws near, the event has officially announced the highly anticipated list of “Popular Products & Services.” Among numerous entries, Perotin Bio stood out and was proudly selected.
2026/01/19
From December 26 to 28, 2025, the “2025 Third Advanced Enzyme Engineering and Enzyme Technology Applications Conference,” hosted by the Pharmaceutical Chemicals Professional Committee of the China Chemical Enterprise Management Association and organized by the Zhongke Kaisheng (Beijing) Institute of Chemical Technology, was grandly held in Hangzhou. With the core mission of advancing innovation in enzyme engineering technologies and their industrial implementation, the conference brought together leading industry experts, corporate representatives, and researchers from academic and research institutions, fostering in-depth discussions on key topics such as enzyme molecular design, process optimization, and cross‑disciplinary applications.
2026/01/09
In the modern pharmaceutical industry, most small-molecule drug discovery efforts rely on natural products, which are regarded as the most efficient source of new therapeutics. Many life-saving drugs originate from nature, including steroids, polyketides, nonribosomal peptides, terpenes, and alkaloids. Traditionally, natural products have been obtained through two main approaches: production in heterologous hosts or chemical synthesis. However, both methods often face challenges such as low efficiency, long timelines, and high costs. For example, paclitaxel (Taxol), an important anticancer agent, requires first synthesizing its precursor in cell cultures and then carrying out subsequent organic transformations—a process that is both laborious and expensive.
2026/01/09
免费试用 | 从靶点到药物：珀罗汀全长4次跨膜Claudin-6蛋白，成实体瘤靶向研发“关键利器”
Claudin‑6 is a member of the tight junction protein family, containing four transmembrane domains. It plays an important role during embryonic development and is expressed in fetal tissues such as the stomach, pancreas, lung, and kidney. It is one of the earliest epithelial fate‑determining proteins to be expressed in embryonic stem (ES) cells and serves as a cell‑surface–specific marker for human pluripotent stem cells (HPSCs).
2025/12/24
Recently, the team led by Chen Shi and Wang Lianrong published in Molecular Cell a groundbreaking study titled “The Ppl protein senses 3′-hydroxyl DNA overhangs and NTP depletion to halt phage infection” (DOI: 10.1016/j.molcel.2025.11.011), with an impact factor of 16.6. The research unveils a novel mechanism by which bacteria rely on a single protein to simultaneously monitor two critical signals—3′‑hydroxyl DNA overhangs and NTP depletion—and rapidly activate defense responses during bacteriophage infection, thereby providing a new theoretical foundation for understanding bacterial strategies against phage attacks.
2025/12/17
Perotin Bio’s official LinkedIn account is now live!
To keep our global research partners informed of Perotin Bio’s latest technological advances and product updates, we have officially launched our official LinkedIn account!
2025/12/05
On December 2, 2025, the 2025 GIS Global Innovation Expo and Global Innovation Summit, themed “Pooling Intelligence Worldwide, Co‑Creating a Green Future,” officially opened at the AsiaWorld–Expo in Hong Kong. As a premier technology event bringing together world‑leading scientists, cross‑industry entrepreneurs, and investors, this year’s summit adopted a forward‑looking perspective, focusing on the synergistic development of cutting‑edge fields such as artificial intelligence, biomanufacturing, and green technologies, thereby establishing a high‑end platform for exploring pathways that integrate technological innovation with sustainable development. Among the participants, PLD Technology, a pioneer in cell‑free protein expression, was invited to exhibit, showcasing its portfolio of products and services centered on cell‑free protein expression technology to researchers, industry partners, and investment institutions worldwide. With its hallmark features of “high efficiency and low resource consumption,” PLD Technology offers state‑of‑the‑art solutions to drive the green transformation of biological R&D and accelerate global life‑science innovation.
2025/12/05
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