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Recently, the team led by Chen Shi and Wang Lianrong published in Molecular Cell a groundbreaking study titled “The Ppl protein senses 3′-hydroxyl DNA overhangs and NTP depletion to halt phage infection” (DOI: 10.1016/j.molcel.2025.11.011), with an impact factor of 16.6. The research unveils a novel mechanism by which bacteria rely on a single protein to simultaneously monitor two critical signals—3′‑hydroxyl DNA overhangs and NTP depletion—and rapidly activate defense responses during bacteriophage infection, thereby providing a new theoretical foundation for understanding bacterial strategies against phage attacks.
2025/12/17
Perotin Bio’s official LinkedIn account is now live!
To keep our global research partners informed of Perotin Bio’s latest technological advances and product updates, we have officially launched our official LinkedIn account!
2025/12/05
On December 2, 2025, the 2025 GIS Global Innovation Expo and Global Innovation Summit, themed “Pooling Intelligence Worldwide, Co‑Creating a Green Future,” officially opened at the AsiaWorld–Expo in Hong Kong. As a premier technology event bringing together world‑leading scientists, cross‑industry entrepreneurs, and investors, this year’s summit adopted a forward‑looking perspective, focusing on the synergistic development of cutting‑edge fields such as artificial intelligence, biomanufacturing, and green technologies, thereby establishing a high‑end platform for exploring pathways that integrate technological innovation with sustainable development. Among the participants, PLD Technology, a pioneer in cell‑free protein expression, was invited to exhibit, showcasing its portfolio of products and services centered on cell‑free protein expression technology to researchers, industry partners, and investment institutions worldwide. With its hallmark features of “high efficiency and low resource consumption,” PLD Technology offers state‑of‑the‑art solutions to drive the green transformation of biological R&D and accelerate global life‑science innovation.
2025/12/05
Recently, Perotin Bio leveraged a cell-free protein expression system to successfully produce highly active human SSTR2 membrane protein. Using surface plasmon resonance, the team conducted precise affinity measurements, revealing an exceptionally high binding affinity for the corresponding antibody, with a KD value of 0.649 nM.
2025/11/18
PLD Technology has launched CB2, a full-length transmembrane protein product that fully preserves CB2’s native seven‑transmembrane topology and its ligand‑binding and signal‑transduction activities. With a purity exceeding 85%, it can be directly employed in high‑throughput drug screening, structural biology studies, and antibody development, providing a highly reliable tool to support mechanistic research on related diseases and the discovery of novel therapeutics.
2025/11/18
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